Paris—London—Rom. VIII1)

PHOTODEHYDROCYCLIZATIONS OF STILBENE-LIKE COMPOUNDS VIII1 Synthesis of hexaheliceno[3,4-c]hexahelicene

PHOTODEHYDROCYCLIZATIONS OF STILBENE-LIKE COMPOUNDS VIII1 Synthesis of hexaheliceno[3,4-c]hexahelicene BY

Part IX . A New Diterpene Alcohol from cyptomria D . Don

In continuation of earlier works1) an unknown compound, C20H340, m・P・ 182~183。, [α]15D +14.52°,obtained from the neutral portion of wooe resin of Cryptmeria japonica D. Don, has been examined. In part VIII1) of this series, an isolation of this compound has been described in detail. This compound, called phyllocladanol, is not apparent to have been previously isolated. Phyllocladanol is colorle...

Chromogenic Factor IX Assay for Clinical Use

A chromogenic factor IX assay is developed which requires only two timedependent steps. Diluted plasma is mixed with a reagent containing factors VIII and X. The reaction is started by addition of a reagent containing factor XI", thrombin, CaCl2, and phospholipids. Then factor XIu activates factor IX if present, thrombin activates factor VIII, and subsequently the complete factor X activating c...

NEOPLASIA Bone Marrow Neovascularization, Plasma Cell Angiogenic Potential, and Matrix Metalloproteinase-2 Secretion Parallel Progression of Human Multiple Myeloma

To assess whether the progression of plasma cell tumors is accompanied by angiogenesis and secretion of matrixdegrading enzymes, bone marrow biopsy specimens from 20 patients with monoclonal gammopathy of undetermined significance (MGUS), 18 patients with nonactive multiple myeloma (MM), and 26 patients with active MM were evaluated for their angiogenic potential and matrix-metalloproteinase (M...